… To extend our knowledge of the thiazole ring as a suitable mimic for the cis-olefin present
in combretastatin A-4, we fixed the 3,4,5-trimethoxyphenyl at the C4-position of the thiazole …

… 3,4,5-trimethoxyphenyl thiazole pyrimidines has been synthesized and biologically evaluated
… of anticancer agents and generate new TMP thiazole derivatives with good anticipated …

… Our results indicate that thiazole-based chalcones could be … are needed to obtain highly
potent anticancer agents. … ,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents …

… Herein, we describe our efforts for the synthesis of thiazole-based novel molecules through
a multistep synthetic approach and discovery of promising anticancer hits. Firstly, the thiazole…

… -2-ones 3 and 3-(4-amino-2-(arylamino) thiazole-5-carbonyl)-2H-chromen-2-ones 4 as new
anticancer agents. The target … ′,5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents …

… Among them, tubulin has now become an attractive target for anti-tumor drugs [59]. In …
of the thiazole ring and gained the 2-substituted-4(3’,4’,5’-trimethoxy-phenyl)-5-aryl thiazole …

… 4i warrants further evaluation as a potential anticancer drug. … Here we describe replacing
the thiazole nucleus with the less … groups as the 3′,4′,5′-trimethoxyphenyl moiety, identical …

… having a 2,4-disubstituted thiazole ring were reported to have anticancer activity as well as
… [ Citation 36–42 ] Clinically available thiazole-containing anticancer drugs act as inosine 5′-…

… 3). The phenyl group on 4-position of thiazole ring mimics the three methoxy phenyl moiety
… aromatic ring in the 5-position of the thiazole ring establishes a π–π interaction with Asn258 …

… In summary, we synthesized and evaluated a novel series of thiazole linked chalcone analogs
as anticancer agents. Many of these thiazole analogs showed significant antiproliferative …